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Variable
Univariate analysis
Multivariate Model A
Multivariate Model B
Multivariate Model C
RR (95% CI)
P value
RR (95% CI)
P value
RR (95% CI)
P value
RR (95% CI)
P value
Semen volume (mL)
2.1 (0.96–4.8)
0.065
2.01 (0.87–4.6)
0.100
–
–
2.84 (0.76–10.6)
0.120
Ratio of PR sperm (%)
1.2 (0.75–1.9)
0.450
1.19 (0.66–2.10)
0.552
–
–
1.11 (0.50–2.5)
0.790
Ratio of PR + NP sperm (%)
0.99 (0.58–1.7)
0.960
0.70 (0.30–1.60)
0.398
–
–
0.72 (0.27–2.0)
0.523
Sperm concentration (106 /ml)
1.2 (0.65–2.2)
0.560
1.28 (0.54–3.00)
0.576
–
–
1.45 (0.51–4.1)
0.490
Ratio of morphologically normal sperm (%)
0.9 (0.56–1.4)
0.670
0.91 (0.57–1.50)
0.713
–
–
1.08 (0.56–2.1)
0.825
E2
1.6 (0.64–4.1)
0.310
–
–
0.49 (0.17–1.40)
0.180
0.57 (0.18–1.8)
0.337
PRL
0.98 (0.51–1.9)
0.940
–
–
1.17 (0.55–2.50)
0.681
1.30 (0.57–3.0)
0.531
Serum leptin (μg/L)
1.3 (0.76–2.2)
0.340
–
–
0.74 (0.37–1.50)
0.387
0.49 (0.20–1.2)
0.118
Seminal leptin (μg/L)
1.2 (0.72–2.1)
0.440
–
–
1.90 (0.95–3.8)
0.071
2.29 (1.02–5.1)
0.044
TC (mmol/L)
0.035
< 5.18
1.00
–
–
1.00
1.00
≥ 5.18 & ≤ 6.19
−0.12 (1.2–4.1)
–
–
3.46 (1.35–8.90)
0.010
4.99 (1.75–14.2)
0.003
> 6.2
−0.12 (0.46–1.7)
–
–
0.51 (0.11–2.40)
0.397
0.72 (0.14–3.6)
0.686
LDL-C (mmol/L)
0.930
< 3.37
1.00
–
–
1.00
1.00
≥ 3.37 & ≤ 4.12
−0.034 (0.56–2.3)
–
–
0.57 (0.20–1.60)
0.297
0.38 (0.11–1.3)
0.113
> 4.14
−0.034 (0.46–2)
–
–
1.35 (0.24–7.6)
0.730
1.56 (0.31–8.0)
0.592
HDL-C (mmol/L)
0.380
< 1.04
1.00
–
–
1.00
1.00
≥ 1.04 & < 1.55
0.69 (0.77–2.1)
–
–
1.55 (0.85–2.8)
0.153
1.26 (0.64–2.5)
0.504
≥ 1.55
0.69 (0.68–5.8)
–
–
3.01 (0.78–11.6)
0.109
4.17 (0.96–18.0)
0.056
TG (mmol/L)
0.91 (0.55–1.5)
0.700
–
–
0.84 (0.48–1.5)
0.534
0.79 (0.41–1.5)
0.463
