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Table 1 Demographic and main treatment characteristics for women with singleton live births according to endometrial thickness

From: Thin endometrium is associated with the risk of hypertensive disorders of pregnancy in fresh IVF/ICSI embryo transfer cycles: a retrospective cohort study of 9,266 singleton births

Characteristics EMT ≤ 8 mm 8 < EMT ≤ 12 mm EMT > 12 mm P value
  (n = 544) (n = 6234) (n = 2488)  
Age (y)abc 32.39 ± 4.43 30.91 ± 4.30 30.46 ± 4.33 < 0.001e
BMI (kg/m2) 23.55 ± 3.36 23.50 ± 3.55 23.69 ± 3.65 NSe
Parity, n (%) ab < 0.001f
 First 362 (66.5) 4800 (77.0) 1912 (76.8)  
 High order 182 (33.5) 1434 (23.0) 576 (23.2)  
 Primary infertility, n (%) abc 167 (30.7) 2982 (47.8) 1340 (53.9) < 0.001f
Cause of infertility, n (%) abc < 0.001f
 Oviduct factors 241 (44.3) 1844 (29.6) 668 (26.8)  
 Male factor 128 (23.5) 1749 (28.1) 745 (29.9)  
 Ovulation problems 20 (3.7) 321 (5.1) 120 (4.8)  
 Multiple causes 43 (7.9) 896 (14.4) 364 (14.6)  
 Unexplained 67 (12.3) 872 (14.0) 351 (14.1)  
 Other 45 (8.3) 552 (8.9) 240 (9.6)  
Type of ART treatment, n (%) NSf
 IVF 396 (72.8) 4476 (71.9) 1755 (70.5)  
 ICSI 148 (27.2) 1758 (28.2) 733 (29.5)  
Ovarian stimulation protocol, n (%) c < 0.001f
 GnRH antagonist protocol 102 (18.8) 1153 (18.5) 405 (16.3)  
 GnRH agonist long protocol 202 (37.1) 3183 (51.1) 1519 (61.1)  
 GnRH agonist short protocol 187 (34.4) 1580 (25.3) 444 (17.8)  
 GnRH agonist super long protocol 37 (6.8) 275 (4.4) 112 (4.5)  
 Other protocol 16 (2.9) 43 (0.7) 8 (0.3)  
 EMT on HCG trigger day, (mm)abc 7.57 ± 0.71 10.52 ± 1.06 13.38 ± 1.11 < 0.001d
 Progesterone level on HCG trigger day (ng/mL) ac 0.77 ± 0.37 0.82 ± 0.35 0.80 ± 0.34 0.001e
 E2 level on HCG trigger day (pg/mL) 2856.69 ± 1442.43 2878.68 ± 1431.83 2952.69 ± 1455.60 NSe
Number of embryos transferred, n (%) ab 0.002f
 1 210 (38.6) 1952 (31.3) 782 (31.4)  
 2 334 (61.4) 4282 (68.7) 1706 (68.6)  
 Blastocyst transfer, n (%) 165 (30.3) 1603 (25.7) 632 (25.4) 0.05f
  1. Values are presented as mean ± standard deviation or n (%). ANOVA analysis of variance, BMI body mass index, EMT endometrial thickness, HCG human chorionic gonadotropin, E2 estradiol, NS not statistically significant
  2. aStatistically significant differences between EMT ≤8 and 8 < EMT ≤12 mm groups
  3. bStatistically significant differences between EMT ≤8 mm and EMT > 12 mm groups
  4. cStatistically significant differences between 8 < EMT ≤12 mm and EMT > 12 mm groups
  5. dWelch’s ANOVA
  6. eOne-way ANOVA
  7. fPearson chi-square test
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Reproductive Biology and Endocrinology

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